Geothermal power generation and mineral extraction from geothermal brines are affected by chemical processes within the reservoir. Until recently, numerical simulation technology for geothermal systems could not handle most chemical processes, except for tracking total salinity, one or two non-condensable gases, and non-reactive tracers. The Lawrence Berkeley National Laboratory (LBNL) has developed an enhanced version of their geothermal reservoir simulation software TOUGH2, developed with funding from the U.S. Department of Energy. This highly innovative software (TOUGHREACT) includes comprehensive chemical interactions between liquid, gaseous and solid phases that are coupled to the modeling of solute transport and subsurface multiphase fluid and heat flow.